Hormones are the most powerful molecules in our bodies, controlling the function, growth reproduction, metabolism, and repair of
every cell.
Our bodies require optimal hormone levels, just as they require optimal levels of essential vitanutrients: vitamins,
fats, amino acids, and minerals. Our hormone levels generally are optimal in our youthful years--our early twenties--but begin to
fall soon afterwards and continue to decline with increasing age. Hormone levels decline because our glands and the parts of our
brain that control our glands deteriorate with age. This age-related hormone loss is pre-programmed and unavoidable. It is
natural, but it is not good for us. It is one of mechanisms of
aging--our euphemism for the destructive process by which Nature
causes our deterioration and death in order to remove individuals from the gene pool so that the species can adapt.

Insufficient hormone levels have been shown to contribute to many disorders and diseases--diabetes, atherosclerosis, high blood
pressure, fatigue, loss of muscle strength, osteoporosis, autoimmune diseases, cognitive decline, increased cholesterol levels,
blood clots, increased belly fat, loss of libido, anxiety, depression, and some cancers. In addition to age-related losses, many
persons have hormone insufficiencies or imbalances due to hypothalamic-pituitary dysfunction, endocrine gland failure, hormone
resistance and metabolic disorders.
Women are especially affected by hormonal disorders because their complex hormonal
system is adapted to produce and feed babies; not to optimize their vitality as in men. Women have a much higher incidence of

cortisol deficiency than men
(fatigue, aches, insomnia, anxiety, depression, hypoglycemia, low blood pressure, PMDD,
allergies, and autoimmune diseases). They also have more
hypothyroidism (fatigue, aches, cold hands and feet, dry skin, weight
gain, constipation). Women then suffer ovarian failure at menopause, losing almost all of their estradiol, progesterone, and
testosterone. Women are being poorly served by the prevailing ignorance concerning hormones.  

Conventional medicine today grossly underestimates the importance of optimal hormone levels. It remains
stuck in the mid-20th century. Endocrinologists are taught only to recognize and treat
severe hormonal deficiencies caused by
some identifiable
disease, and to provide only enough hormone replacement to "normalize" certain tests. They claim to practice
clinical endocrinology, but are actually taught to ignore the patient's signs and symptoms and all the complexities of the endocrine
system. They practice "
Reference Range Endocrinology"; accepting any hormone level anywhere within the laboratory's
reference range as "normal", meaning "no disease". They fail to understand that persons have various degrees of hormone
resistance. They fail to understand the interactions among hormones. They fail to understand that the laboratory ranges include
95% of a group of "apparently healthy" adults who were
not screened for symptoms. The reference range includes almost
everyone! Worse, they ignore a person's actual thyroid levels and symptoms and rely almost entirely on the TSH test to determine
their thyroid hormone status. This illogical
TSH-T4 thyroidology makes them incapable or diagnosing or properly treating most
hypothyroidism. Physicians function under the delusion that a "normal' TSH means "euthyroidism". They treat a high TSH with just
enough levothyroxine to "normalize" the TSH, a practice that has been repeatedly shown to fail to restore physiological
euthyroidism.  TSH-normalization with T4 can leave many persons markedly hypothyroid. Doctors then blame their patients'
persisting hypothyroid symptoms on depression, "chronic fatigue", "fibromyalgia", hypochondria or bad habits. Because of the
inappropriate belief in the Immaculate TSH, even the laboratory ranges for free T4 and free T3 are wrong. Labs include test
results from TSH-normal hospital and clinic patients. So the FT4 and FT3 ranges are actually ill-patient ranges! In fact, most
hormone deficiencies not due to failure of the gland--except for menopause. Most deficiencies
partial central hormone
--caused by hypothalamic-pituitary dysfunction--and partial resistance syndromes caused by genetic mutations of
enzymes, receptors and other proteins needed for hormone action in the tissues. Most hypothyroidism is due to inadequate TSH
production and genetic mutations, not thyroid gland disease. Worse, endocrinologists are practically incapable of diagnosing or
cortisol deficiency. Read Dr. Lindner's submission to the Scottish Parliament for a brief summary of the failures of
conventional endocrinology, the causes of these failures, and the legal reforms that are necessary to assure that the population
has access to effective endocrine care.

One of the causes of this hormone ignorance is the influence of pharmaceutical corporations in medicine. Big Pharma downplays
the importance of hormones and encourages doctors to prescribe drugs for every symptom. For "hormone therapy", it promotes
patented hormone-like drugs ("steroids", estrogens, progestins, etc.) instead of the correct, non-patentable bioidentical (human)
molecules. Big Pharma attacks compounding pharmacies because they are the competition and they inform women of the
necessity of using the correct molecules. When pharmaceutical hormone substitutes cause serious diseases and disorders,
physicians believe that human hormones are dangerous. However, the evidence indicates that
restoring human hormones by
the correct route, and in correct balance with other hormones, provides all the
natural benefits of the hormones without the
that occur with pharmaceutical hormone substitutes and approaches. For instance, transdermal estradiol does not
increase the risks of blood clots and strokes like oral estrogen tablets do.
Progesterone has a protective effect against breast
cancer, whereas many progesterone-substitutes (progestins) promote breast cancer.
Cortisol restoration at physiological
doses, and accompanied by
DHEA, does not have the long term negative effects of "steroids" like prednisone and Medrol. Human
hormones have no "side effects" by definition! For certain, even bioidentical-human hormone replacement can cause problems
when given in the
wrong way, in excessive doses, or without proper balance with other hormones. However, the fact that
something can be done wrong does not mean that it can't be done right.

As a result of false assumptions and pharmaceutical contamination, endocrinology is an ineffective, moribund specialty; dominated
hormone myths. Imagine it--because of decades of inappropriate hormone substitution therapy for women  (e.g. Prempro),  
endocrinologists believe that a woman's own hormones--which have maintained her health and well-being all her life--somehow
become dangerous at age 50. They believe that ovarian failure should not be treated. Menopause is natural, but it is also an
endocrine catastrophy--seriously eroding a woman's quality of life and health. Every physician is ethically-obligated to
treat a woman's ovarian failure, should she so request.
She must demand transdermal estradiol, oral, sublingual,
transdermal or vaginal
progesterone, and transdermal, vaginal or subcutaneous testosterone. Estradiol and progesterone are
available in FDA-approved forms, whereas transdermal testosterone must be pharmacy-compounded. Women can use
testosterone products that are FDA-approved for men--but at much smaller doses. Menopausal women can read, and refer their
physicians to pages 59 to 68 of
Sex-Steroid Restoration for Women for guidance concerning products and doses.

To be an effective physician one must become adept at recognizing partial, functional, and age-related hormone deficiencies and
at optimizing hormone levels and effects for every patient--this is a foundation of good medical practice. It's really just

  • Optimal hormone levels are vital to our health and vitality.
  • The disorders and diseases caused by partial hormone deficiencies are well-known and serious.
  • Balanced hormone optimization prevents and treats these disorders and improves quality of life.
  • The scientific evidence indicates that balanced hormone restoration improves health and quality of life and
    does not cause harm.

Medical practice, which is now essentially a pharmaceutical disease-drug scheme, should be based upon an entirely different
conceptual foundation--that of detecting the biomolecular
causes of symptoms and disorders, and fixing the problem by optimizing
the amounts and balance of the important molecules that are innate to the body--among them hormones and vitanutrients. We
need a new paradigm in endocrinology--
"Restorative Endocrinology":

  • Restoring optimal hormone levels is essential preventative medicine.
  • Restoring optimal hormone levels is essential to the treatment of all diseases.
  • Restoring optimal hormone levels is essential to our Quality of Life!
Hormone Restoration for
Health and Quality of Life
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Feb 1, 2007
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