Dear Women: Menopause is natural, but it is an endocrine catastrophe--the complete failure of your major sex-steroid
producing gland. It is equivalent to a man losing his testes. Menopause is natural, but it is the result of an evolutionary
compromise. It prevents more pregnancies so that women can assure the survival of their existing children. Imagine the
contrary--if women remained fertile their entire life! Your ovarian hormones were essential to your health and quality of life
before menopause and they remain so after menopause.
Ovarian hormone replacement is not dangerous--it is vital to
your health and quality of life
. What has been shown to be dangerous is the use of non-human hormone substitutes like
Premarin and Provera (PremPro).
Human bioidentical molecules, delivered by the correct route and in correct balance
with other hormones provide all the
natural benefits without the risks seen with non-human molecules. Transdermal
estradiol
does not increase the risks of blood clots and strokes like oral estrogen tablets do. Progesterone counteracts
estradiol in the breasts and uterus, reduces proliferation in those tissues, and therefore the combination of estradiol and
progesterone does not increase the growth of cancers in those organs. On the contrary,
Provera and many other
progesterone-substitutes (progestins)
promote breast cancer. Testosterone restoration to youthful levels is beneficial for
your mood, libido, energy and muscle strength and causes no health problems. Testosterone also antagonizes estradiol in the
breasts, reducing proliferation and the risk of breast cancer.
You have the right to demand that your ovarian failure be
treated. Your physician is ethically obligated to provide ovarian hormone replacement if you so demand.
Estradiol
and progesterone are available in FDA-approved forms from any pharmacy, and from compounding pharmacies, whereas
transdermal testosterone must compounded. You can demand transdermal
estradiol in either FDA-approved gels and
patches from regular pharmacies or in a cream from a compounding pharmacy. You must also demand
progesterone,
whether you still have your uterus or not. Progesterone is available in FDA-approved capsules and in creams and
sublingual/vaginal tablets from compounding pharmacies. The FDA-approved capsules are most effective if inserted vaginally
rather than swallowed. You can only get testosterone from a compounding pharmacy as "women's advocates" prevented the
FDA from approving a testosterone patch for women. Your doctor can call a compounding pharmacy for the appropriate
testosterone product and dose. You should read, and refer your physician to, my powerpoint
Sex-Steroid Restoration for
Women. Pages 59 to 68 contain detailed guidance concerning the use of both FDA-approved and compounded hormone
products and doses.

Dear Thyroid Patients: If you have thyroid gland failure--primary hypothyroidism--your doctor is giving you a dose of
levothyroxine that normalizes your thyroid stimulating hormone (TSH) level. Abundant research shows that this practice usually

does not restore euthyroidism
--sufficient T3 effect in all tissues of the body. It fails particularly badly in persons who have
had their thyroid gland removed.
TSH is not a thyroid hormone and is not an appropriate guide to thyroid replacement therapy.
The hypothalamic-pituitary secretion of TSH did not evolve to tell physicians what dose of inactive levothyroxine a person
should swallow every day. A low or suppressed TSH on replacement therapy is not the same thing as a low TSH in primary
hyperthyroidism.
IF you continue to suffer from the symptoms of hypothyroidism, you have the right to demand that your
physician give you
more effective T4/T3 (inactive/active) thyroid replacement therapy. Your physician can either add sufficient
T3 (10 to 20mcg
s) to your T4 dose, or lower your T4 dose while adding the T3. The most convenient form of T4/T3 therapy,
with a 4:1 ratio, is
natural desiccated thyroid (NDT-- Armour, NP Thyroid, Nature-Throid). If you have persistent symptoms,
a
sk your physician change you to NDT and adjust the dose to keep the TSH at the bottom of its range-- when you have the
blood drawn in the morning prior to your daily dose. This may be sufficient treatment, but
IF you continue to have persisting
hypothyroid symptoms, and no hyperthyroid symptoms, a
sk your physician to increase the dose to see if your symptoms will
improve, even if the TSH becomes low or suppressed. You can prove to your physician that you're not hyperthyroid by the
facts that you have no symptoms of hyperthyroidism and your free T4 and free T3 levels are normal in the morning, prior to
your daily dose. They may even be below the middle of their ranges. Your free T3 will be high for several hours after your
morning T4/T3 dose, but this is normal with this therapy and produces no problems. You should insist that testing be done

prior
to your daily dose, as recommended by professional guidelines. If you have central hypothyroidism, the TSH will
necessarily be low or completely suppressed on T4/T3 therapy
. In all cases, your physician must treat you according to your
signs and
symptoms first, and the free T4 and free T3 levels second.

If you cannot obtain the sex-hormone, thyroid, or adrenal care from your primary care physician, call local compounding
pharmaices to see if they know of a physician that provides such care. If you cannot obtain such care locally, consider going to
a Holtorf Medical Group clinic (
See website). Fortunately there is a clinic in the Philadelphia area.

Hormones are the most powerful molecules in our bodies, controlling the function, growth reproduction, metabolism, and
repair  of every cell.
Our bodies require optimal hormone levels, just as they require optimal levels of essential
vitanutrients: vitamins, fats, amino acids, and minerals. Insufficient hormone levels have been shown to contribute to many
disorders and diseases--diabetes, atherosclerosis, high blood pressure, fatigue, loss of muscle strength, osteoporosis,
autoimmune diseases, cognitive decline, increased cholesterol levels, blood clots, increased belly fat, loss of libido, anxiety,
depression, and some cancers. In addition to age-related losses, many persons have hormone insufficiencies or imbalances
due to hypothalamic-pituitary dysfunction, endocrine gland failure, hormone resistance and metabolic disorders.
Women are
especially affected by hormonal disorders
because their complex hormonal system is adapted to produce and feed
babies; not to optimize their vitality as in men. Women have a much
higher incidence of hypocortisolism than men
(fatigue, aches, insomnia, anxiety,depression, hypoglycemia, low blood pressure, PMS/PMDD, allergies, and autoimmune
diseases). They also have
more hypothyroidism (fatigue, aches, cold hands and feet, dry skin, weight gain, constipation).
Women then suffer complete
ovarian failure at menopause. Women are being poorly served by the prevailing ignorance
concerning hormones.  

Conventional medicine today grossly underestimates the importance of optimal hormone levels. It remains
disease-oriented,
stuck in the ideas from the early 20th century. Endocrinologists are taught only to recognize and treat
severe hormonal
deficiencies caused by identifiable
disease or damage affecting a gland, and to provide only enough hormone replacement
to "normalize" certain tests. They are actually taught to ignore the patient's signs and symptoms and all the complexities of the
endocrine system. They practice "
Reference Range Endocrinology"; accepting any hormone level anywhere within the
laboratory's reference range as "normal", meaning "no disease". They fail to understand that
population ranges do not
define what is optimal for our species, or for any individual
. The laboratory ranges include 95% of a group of
"apparently healthy" adults who were
not screened for symptoms. They include almost everyone! Worse, physicians ignore
a person's actual thyroid hormone levels and their symptoms and rely almost entirely on the wrong test, the TSH, to diagnose
and treat hypothyroidism. This illogical
TSH-T4 thyroidology makes them incapable of diagnosing or properly treating
hypothyroidism. It has has also corrupted the laboratory ranges for free T4 and free T3. Laboratories include physican-
ordered tests from TSH-normal hospital and clinic patients in their ranges. They are actually sick patient ranges! In fact, most
hormone deficiencies not due to failure of a gland--except for menopause. Most deficiencies are
partial central hormone
deficiencies
--caused by hypothalamic-pituitary dysfunction--and partial resistance syndromes caused by genetic
mutations of enzymes, receptors and other proteins needed for hormone action in the tissues. Endocrinologists are also
practically incapable of diagnosing or treating
cortisol deficiency. Physicians are actually afraid of cortisol. However, cortisol
restoration at physiological doses, and accompanied by
DHEA, does not have the long-term negative effects of "steroids" like
prednisone and Medrol. Human hormones have no "side effects" by definition! For certain, even bioidentical-human hormone
replacement can cause problems when given in the
wrong way, in excessive doses, or without proper balance with other
hormones. Read Dr. Lindner's
submission to the Scottish Parliament for a brief summary of the failures of conventional
endocrinology, their causes, and the legal reforms necessary to assure that the population has access to effective endocrine
care.

Because it still clings to the
old disease-based Reference Range Endocrinology, and because of pharmaceutical
corporation and FDA corruption
, endocrinology is an ineffective, moribund specialty, dominated by hormone myths.
Indeed, all of medical practice is now essentially a
pharmaceutical disease-drug scheme. Medicine requires an entirely
different conceptual foundation: it should first and foremost try to find the biomolecular
causes of all symptoms and disorders,
and should attempt to fix the problems by addressing the causes. In many cases all that is needed is to optimize the amounts
and balance of important natural molecules--among them hormones and vitanutrients. I call the new endocrine paradigm
"Restorative Endocrinology". See my E-book for much more detailed information and advice.
Hormone Restoration for
Health and Quality of Life
Web Site established:
Feb 1, 2007
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Unfortunately, Dr. Lindner's practice is full. He cannot accept new patients.